This is a type of tumors involving the immune system. The lymph nodes in the neck, often with the lymph nodes in other part of the body, are affected and become enlarged nodules. The Enlarged lymph nodes can be found in multiple area of the neck, often in supraclavicular (collarbone) area. They are generally not painful but may be tenderness when pressing. As they progress, several enlarged nodules may merge into a hard tumor becoming visible. There may have other symptoms of cancer such as weight loss, low fever, itching and malaise. Please go to see your doctor for diagnosis and treatments when there is single or multiple swelling lymph nodes.